A New Class of Pyrethroidal Insecticides; α-Substituted Phenylacetic Acid Esters

ACIDITIES OF SOME SUBSTITUTED PHENYLACETIC ACID NITRILES, tert-BUTYL ESTERS AND DIMETHYLAMIDES

The pKAH-values of some substituted phenylacetic acid derivatives have been determined in the system water /dimethyl sulphoxide / 0. 11 M tetramethylammonium hydroxide. The acidity depends strongly on the polarity of the substituent in the phenyl group, Hammett p-valucs from 4.8 to 5 .8, and in the case of the same s<1bstituent decreasf's in the order nit! ik, terr-butyl ester, dimethylami<'e e...

Asymmetric Michael addition of α-fluoro-α-nitro esters to nitroolefins: towards synthesis of α-fluoro-α-substituted amino acids.

α-Fluoro-α-nitro esters were used as reaction partners in Michael addition to nitroalkenes, and the products were obtained in excellent chemical yields and with high enantioselectivities. Moreover, α-fluoro-α-amino ester with a quaternary α-carbon was prepared for the first time.

Conversion of 4-oxoproline esters to 4-substituted pyrrole-2-carboxylic acid esters.

The Grignard, Wittig, Tebbe, Horner-Emmons, and Reformatsky reactions of the 4-oxoproline esters gave the corresponding 4-alylated or 4-alkylidenated products, respectively. The products were properly treated with bases to cause aromatization, giving 4-substituted pyrrole-2-carboxylic acid esters such as methyl 4-methylpyrrole-2-carboxylate, which is a trail pheromone of Atta texana.

NEW DRUGS IN DERMATOLOGY Prof Dr Claude FAVROT A new class of insecticides: Isoxazoline Isoxazoline is a new class of potent insecticides including Fluralaner, afoxolaner and sarolaner

A New Class of Banach Sequence Spaces